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Common supplements and medications could cause liver damage, studies show

(6 months ago)
Melissa Rudy
HealthMedsLifestyleMedresearchVitamins-supplements

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TL;DR: Key points with love ❤️

Experts warn about the increasing incidence of drug-induced liver injury (DILI) caused by common medications, herbal products, and dietary supplements, with specific products like turmeric, kratom, green tea extract, and Garcinia cambogia identified as potential risks, highlighting the need for stricter regulation and awareness.

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  1. 1 1960s: DILI cases began growing in Western countries.
  2. 2 2004-2014: Cases of DILI linked to herbal or dietary supplements nearly tripled (according to a 2024 study).
  3. 3 2024: Study published in JAMA Network Open.
  4. 4 Recent: Research published in Toxicology Reports.
  • Increased risk of liver damage, acute liver failure, and potentially fatal outcomes from common medications and supplements.
  • Calls for greater awareness and potentially stricter regulation.
What: Cases of drug-induced liver injury (DILI) are on the rise, linked to common medications, herbal products, and dietary supplements, with specific concerns raised about turmeric, kratom, green tea extract, and Garcinia cambogia.
When: Article published June 2, 2025. DILI has been growing since the 1960s. Cases linked to HDS nearly tripled between 2004 and 2014 (according to a 2024 study).
Where: Western countries (general), United States (specifically for FDA and DILIN).
Why: The liver's function in metabolizing substances, slower metabolism in some individuals, lack of strict regulation for herbal supplements, and potential toxicity of certain ingredients contribute to the rise in DILI.
How: Studies (Toxicology Reports, JAMA Network Open) identify triggers and trends. Experts like Dr. Marc Siegel explain the mechanisms and risks. The FDA's regulatory approach for supplements differs from drugs.

Experts warn about the increasing incidence of drug-induced liver injury (DILI) caused by common medications, herbal products, and dietary supplements, with specific products like turmeric, kratom, green tea extract, and Garcinia cambogia identified as potential risks, highlighting the need for stricter regulation and awareness.